Cefpodoxime belongs to the third-generation antibiotics. It is effective against gram-positive and gram-negative bacteria. It is prodrug which after absorption undergoes de-esterification in the intestinal mucosa. It is resistance against beta lactamase enzyme produced by the bacteria.
Community acquired pneumonia
Uncomplicated skin and subcutaneous tissue bacterial infections
Otitis media
Gonorrhoea
Bacterial infections
Cefpodoxime inhibits the synthesis of cell wall by inhibiting the peptidoglycan mediated crosslinking of N-acetyl glucosamine and N-acetyl muramic acid.
Absorption-
It is absorbed orally by gastrointestinal tract
Protein Binding-
It is 23% bound to plasma proteins
Metabolism-
It does not show metabolism
Excretion-
It is excreted unchanged via urine
Bloating
Body aches
Back pain
Anxiety
Tightness in chest
Chills
Weakness
Contraindicated in people with known allergy
Aspirin
Azithromycin
Amoxicillin
Cefuroxime
Furosemide
| Cefpodoxime Proxetil | 100 mg |